Development of Probiotic Formulations for Oral Candidiasis Prevention: Gellan Gum as a Carrier To Deliver Lactobacillus paracasei 28.4
Abstract
Probiotics might provide an alternative approach for the control of oral candidiasis. However, studies on the antifungal activity of probiotics in the oral cavity are based on the consumption of yogurt or other dietary products, and it is necessary to use appropriate biomaterials and specific strains to obtain probiotic formulations targeted for local oral administration. In this study, we impregnated gellan gum, a natural biopolymer used as a food additive, with a probiotic and investigated its antifungal activity against Candida albicans .
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 21, 2020
- Source ID
- 10.1128/aac.02323-19
Entities
People
- Anita Shukla
- Beth Burgwyn Fuchs
- Eleftherios Mylonakis
- Felipe Ribeiro
- Juliana C Junqueira
- Jéssica Diane Dos Santos
- Patrícia Pimentel De Barros
- Rodnei Dennis Rossoni
- Shashank Shukla
Organizations
- Brown University
- National Council for Scientific and Technological Development
- Office of Naval Research
- São Paulo Research Foundation