Role of DNA Repair and Protective Components in Bacillus subtilis Spore Resistance to Inactivation by 400-nm-Wavelength Blue Light
Abstract
Effective methods of spore inactivation would be of considerable interest in the health care and medical products industries, particularly if the decontamination method effectively killed spores while remaining benign to both humans and sensitive equipment. Intense blue light radiation is one such treatment that has drawn significant interest. In this work, all known spore-protective features, as well as universal and spore-specific DNA repair mechanisms, were tested in a systematic fashion for their contribution to the resistance of spores to blue light radiation.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 01, 2018
- Source ID
- 10.1128/aem.01604-18
Entities
People
- Bahar Djouiai
- Barbara Setlow
- Joanne E. Thwaite
- Peter Setlow
- Prof. Dr. Fabian M. Commichau
- Ralf Moeller
- Thomas R Laws
Organizations
- Army Research Office
- German Aerospace Center
- German Research Foundation
- University of Connecticut Health Center