Exposure of Shewanella oneidensis MR-1 to Sublethal Doses of Ionizing Radiation Triggers Short-Term SOS Activation and Longer-Term Prophage Activation
Abstract
The bacterial minimum threshold of sensitivity to ionizing radiation (IR) is poorly understood, which hinders our understanding of how living systems recover from the doses of IR experienced in medical, industrial, and off-world environments. Using a transcriptome-wide approach, we studied how in the highly radiosensitive bacterium S. oneidensis , genes (including the SOS regulon and the So Lambda prophage) are activated after exposure to low doses of IR.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 29, 2023
- Source ID
- 10.1128/aem.01716-22
Entities
People
- Jacob Blacutt
- Lydia M Contreras
- Philip Sweet
- Vernita D. Gordon
Organizations
- Defense Threat Reduction Agency
- University of Texas at Austin