Burkholderia pseudomallei JW270 Is Lethal in the Madagascar Hissing Cockroach Infection Model and Can Be Utilized at Biosafety Level 2 to Identify Putative Virulence Factors
Abstract
Burkholderia pseudomallei , the causative agent of melioidosis, is classified by the CDC as a tier 1 select agent, and work involving it must be performed in a biosafety level 3 (BSL-3) laboratory. Three BSL-2 surrogate strains derived from B. pseudomallei 1026b, a virulent clinical isolate, have been removed from the CDC select agent list.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 18, 2022
- Source ID
- 10.1128/iai.00159-22
Entities
People
- Arthur M. Friedlander
- David Deshazer
- Ethan Nguyenkhoa
- Jennifer Chua
- Sherry Mou
- Steven A. Tobery
Organizations
- Defense Threat Reduction Agency
- United States Army Medical Research Institute of Infectious Diseases