Development of Melioidosis Subunit Vaccines Using an Enzymatically Inactive Burkholderia pseudomallei AhpC
Abstract
Burkholderia pseudomallei , the causative agent of melioidosis, is a facultative intracellular, Gram-negative pathogen that is highly infectious via the respiratory route and can cause severe, debilitating, and often fatal diseases in humans and animals. At present, no licensed vaccines for immunization against this CDC Tier 1 select agent exist.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 18, 2022
- Source ID
- 10.1128/iai.00222-22
Entities
People
- Alfredo G Torres
- Caitlyn E. Orne
- Lindsey K. Schmidt
- Mary N. Burtnick
- Nittaya Khakhum
- Paul J. Brett
- Shane M. Wilson
- Teresa L. Shaffer
Organizations
- Defense Threat Reduction Agency
- Mahidol University
- University of Nevada, Reno
- University of Texas Medical Branch