H 2 S, a Bacterial Defense Mechanism against the Host Immune Response
Abstract
The biological mediator hydrogen sulfide (H 2 S) is produced by bacteria and has been shown to be cytoprotective against oxidative stress and to increase the sensitivity of various bacteria to a range of antibiotic drugs. Here we evaluated whether bacterial H 2 S provides resistance against the immune response, using two bacterial species that are common sources of nosocomial infections, Escherichia coli and Staphylococcus aureus .
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2019
- Source ID
- 10.1128/iai.00272-18
Entities
People
- Csaba Szabo
- Evgeny Nudler
- Gabor Törö
- Konstantin Shatalin
- Seung-jin Lee
- Tracy Toliver-kinsky
- Weihua Cui
Organizations
- Blavatnik Family Foundation
- Grossman School of Medicine
- Howard Hughes Medical Institute
- National Institutes of Health
- Shriners Hospitals for Children
- United States Department of Defense
- University of Fribourg
- University of Texas Medical Branch