Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection

Abstract

Enterotoxigenic Escherichia coli (ETEC) causes diarrheal illness in infants in the developing world and travelers to countries where the disease is endemic, including military personnel. ETEC infection of the host involves colonization of the small intestinal epithelium and toxin secretion, leading to watery diarrhea.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 01, 2018
Source ID
10.1128/iai.00355-18

Entities

People

  • Danielle Wisheart
  • Eileen M. Barry
  • Jessica R. Pondish
  • Lisa A. Cavacini
  • Maja Sedic
  • Mark S. Klempner
  • Matteo Stoppato
  • Monir Ejemel
  • Serena Giuntini
  • William D. Thomas Jr.
  • Yang Wang
  • Zachary A. Schiller

Organizations

  • Centre Pour le Développement des Vaccins-Mali
  • Gates Foundation

Tags

Fields of Study

  • Biology

Readers

  • Immunology
  • Microbial Pathology