Establishment and Validation of Pathogenic CS17 + and CS19 + Enterotoxigenic Escherichia coli Challenge Models in the New World Primate Aotus nancymaae

Abstract

Enterotoxigenic Escherichia coli (ETEC) is a common cause of diarrheal illness in the military, travelers, and children living in low- to-middle income countries. Increased antibiotic resistance, the absence of a licensed vaccine, and the lack of broadly practical therapeutics perpetuate the significant health and financial burden resulting from ETEC infection.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 16, 2021
Source ID
10.1128/iai.00479-20

Entities

People

  • Aisling O’dowd
  • Eric Hall
  • Gladys Nunez
  • Julianne E. Rollenhagen
  • Nereyda Espinoza
  • Stephen J. Savarino

Organizations

  • Congressionally Directed Medical Research Programs
  • Henry M. Jackson Foundation for the Advancement of Military Medicine
  • Naval Medical Research Center
  • Uniformed Services University of the Health Sciences

Tags

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Microbial Pathology
  • Parasitology and Pharmacology of Malaria.

Technology Areas

  • Biotechnology