Persistence Alters the Interaction between Chlamydia trachomatis and Its Host Cell
Abstract
In response to stress, the obligate intracellular pathogenChlamydia trachomatisstops dividing and halts its biphasic developmental cycle. The infectious, extracellular form of this bacterium is highly susceptible to killing by the host immune response, and by pausing development,Chlamydiacan survive in an intracellular, “aberrant” state for extended periods of time.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 15, 2021
- Source ID
- 10.1128/iai.00685-20
Entities
People
- George W Liechti
- Mary R. Brockett
Organizations
- National Institute of General Medical Sciences
- Uniformed Services University of the Health Sciences