Formaldehyde-Responsive Proteins TtmR and EfgA Reveal a Trade-off between Formaldehyde Resistance and Efficient Transition to Methylotrophy in Methylorubrum extorquens
Abstract
All organisms produce formaldehyde as a by-product of enzymatic reactions and as a degradation product of metabolites. The ubiquity of formaldehyde in cellular biology suggests all organisms have evolved mechanisms of mitigating formaldehyde toxicity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 08, 2021
- Source ID
- 10.1128/jb.00589-20
Entities
People
- Christopher J Marx
- Eric L Bruger
- Jannell V Bazurto
- Jessica A Lee
- Leah B. Lambert
Organizations
- Ames Research Center
- Army Research Office
- National Institutes of Health
- National Science Foundation
- University of Idaho
- University of Minnesota