Serum-Based Diagnosis of Pediatric Tuberculosis by Assay of Mycobacterium tuberculosis Factors: a Retrospective Cohort Study
Abstract
Diagnosis of pediatric tuberculosis (TB) is often complicated by its nonspecific symptoms, paucibacillary nature, and the need for invasive specimen collection techniques. However, a recently reported assay that detects Mycobacterium tuberculosis virulence factors in serum can diagnose various TB manifestations, including paucibacillary TB cases, in adults with good sensitivity and specificity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 21, 2021
- Source ID
- 10.1128/jcm.01756-20
Entities
People
- Chang Liu
- Christopher J. Lyon
- Duc T Nguyen
- Edward A Graviss
- Tony Y. Hu
- Wei Sha
- Yifan He
Organizations
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Houston Methodist Hospital
- National Institute of Allergy and Infectious Diseases
- Tulane University of Louisiana
- United States Department of Defense
- University of South Carolina