Headless Henipaviral Receptor Binding Glycoproteins Reveal Fusion Modulation by the Head/Stalk Interface and Post-receptor Binding Contributions of the Head Domain
Abstract
The Henipavirus genus in the Paramyxoviridae family includes the zoonotic Nipah (NiV) and Hendra (HeV) viruses. NiV and HeV infections often cause fatal encephalitis and pneumonia, but no vaccines or therapeutics are currently approved for human use.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 27, 2021
- Source ID
- 10.1128/jvi.00666-21
Entities
People
- Amandine Gamble
- David W. Buchholz
- Hector C Aguilar
- Mason Jager
- Yao Yu Yeo
Organizations
- Cornell University
- National Institute of Allergy and Infectious Diseases
- University of California, Los Angeles