Beta Human Papillomavirus 8 E6 Induces Micronucleus Formation and Promotes Chromothripsis
Abstract
Some beta genus human papillomaviruses (β-HPVs) may promote skin carcinogenesis by inducing mutations in the host genome. Supporting this, the E6 protein from β-HPV8 (8 E6) promotes skin cancer in mice with or without UV exposure.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 12, 2022
- Source ID
- 10.1128/jvi.01015-22
Entities
People
- Dalton Dacus
- Elizabeth Rifrogiate
- Nicholas A Wallace
- Rachel Palinski
- Sarah R. Pollina
- Steven Stancic
Organizations
- Kansas State University
- National Institutes of Health
- United States Department of Defense