Gammaherpesvirus RNAs Come Full Circle
Abstract
After an adaptive immune response is mounted, gammaherpesviruses achieve persistence through the utilization of viral noncoding RNAs to craft a suitable host cell environment in an immunologically transparent manner. While gammaherpesvirus long noncoding RNAs (lncRNAs) and microRNAs have been recognized for some time and have been actively investigated, a recent spate of reports have now identified repertoires of the circular RNA (circRNA) class of noncoding RNAs in both the lymphocryptovirus and rhadinovirus genera of gammaherpesviruses.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 30, 2019
- Source ID
- 10.1128/mbio.00071-19
Entities
People
- Erik K Flemington
- Nathan A. Ungerleider
- Rolf Renne
- Scott A. Tibbetts
Organizations
- National Institutes of Health
- Tulane University of Louisiana
- United States Department of Defense
- University of Florida