An Infection-Tolerant Mammalian Reservoir for Several Zoonotic Agents Broadly Counters the Inflammatory Effects of Endotoxin

Abstract

Animals that are natural carriers of pathogens that cause human diseases commonly manifest little or no sickness as a consequence of infection. Examples include the deer mouse, Peromyscus leucopus , which is a reservoir for Lyme disease and several other disease agents in North America, and some types of bats, which are carriers of viruses with pathogenicity for humans.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 27, 2021
Source ID
10.1128/mbio.00588-21

Entities

People

  • Alan G. Barbour
  • Ali Mortazavi
  • Ana Milovic
  • Gabriela Balderrama-Gutierrez
  • Hippokratis Kiaris
  • John T Belisle
  • M Nurul Islam
  • Vanessa J Cook
  • Youwen Zhang

Organizations

  • Colorado State University
  • Global Lyme Alliance
  • National Institute of Allergy and Infectious Diseases
  • National Science Foundation
  • United States Department of Defense
  • University of California, Irvine
  • University of South Carolina

Tags

Readers

  • Infectious Disease/Epidemiology
  • Toxicology/Environmental Toxicology