Cellulosome Localization Patterns Vary across Life Stages of Anaerobic Fungi

Abstract

Anaerobic fungi ( Neocallimastigomycota ) isolated from the guts of herbivores excel at degrading ingested plant matter, making them attractive potential platform organisms for converting waste biomass into valuable products, such as chemicals and fuels. Major contributors to their biomass-hydrolyzing power are the multienzyme cellulosome complexes that anaerobic fungi produce, but knowledge gaps in how cellulosome production is controlled by the cellular life cycle and how cells spatially deploy cellulosomes complicate the use of anaerobic fungi and their cellulosomes in industrial bioprocesses.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 29, 2021
Source ID
10.1128/mbio.00832-21

Entities

People

  • Charles H. Haitjema
  • Chuck R. Smallwood
  • James E Evans
  • Michelle O'Malley
  • Sean P. Gilmore
  • Stephen P Lillington
  • Vaithiyalingam Shutthanandan
  • William Chrisler

Organizations

  • Army Research Office
  • Environmental Molecular Sciences Laboratory
  • Sandia National Laboratories
  • United States Department of Energy
  • University of California, Santa Barbara
  • Washington State University

Tags

Fields of Study

  • Biology

Readers

  • Aquatic Ecology
  • Microbial Pathology
  • Systems Analysis and Design