Dietary Fiber Hierarchical Specificity: the Missing Link for Predictable and Strong Shifts in Gut Bacterial Communities

Abstract

In the face of interindividual variability and complexity of gut microbial communities, prediction of outcomes from a given fiber utilized by many microbes would require a sophisticated comprehension of all competitive interactions that occur in the gut. Results presented here suggest that high-specificity fibers potentially circumvent the competitive scope in the gut for fiber utilization, providing a promising path to targeted and predictable microbial shifts in different individuals.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 29, 2021
Source ID
10.1128/mbio.01028-21

Entities

People

  • Ali Keshavarzian
  • Andrea Ruthes
  • Bruce R Hamaker
  • Eponine Chambry
  • Marcello Iacomini
  • Nuseybe Bulut
  • Thaisa M. Cantu-jungles
  • Timothy A. Johnson

Organizations

  • Purdue University
  • Rush University
  • United States Department of Defense
  • Universidade Federal do ParanĂ¡

Tags

Fields of Study

  • Biology

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Systems Analysis and Design
  • Theoretical Analysis.

Technology Areas

  • Biotechnology