Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response

Abstract

Bacterial antibiotic persistence is a transient physiological state wherein cells become dormant and thereby evade being killed by antibiotics. Once the antibiotic is removed, bacterial persisters are able to resuscitate and repopulate.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 29, 2021
Source ID
10.1128/mbio.01132-21

Entities

People

  • Jesse Rinehart
  • Kyle Mohler
  • Michael Ibba
  • Whitney N. Wood

Organizations

  • Army Research Office
  • Chapman University
  • National Institutes of Health
  • Ohio State University
  • Yale School of Medicine
  • Yale University

Tags

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Microbial Pathology
  • Molecular and Cellular Biochemistry