Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop
Abstract
Ebola virus remains a global threat to public health and biosecurity, yet we still know relatively little about its pathogenesis and the complications that arise following recovery. With nearly 20,000 survivors from the 2013–2016 West African outbreak, as well as over 1,000 survivors of the recent outbreak in the DRC, we must consider the consequences of virus persistence and recrudescent disease, even if they are rare.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 23, 2021
- Source ID
- 10.1128/mbio.01438-20
Entities
People
- Anders Leung
- Carissa Embury-hyatt
- Estella Moffat
- Feihu Yan
- Katie A. Howell
- Keding Cheng
- Krzysztof Franaszek
- Logan Banadyga
- M. Javad Aman
- Shihua He
- Shweta Kailasan
- Vinayakumar Siragam
- Wenguang Cao
- Wenjun Zhu
- Xiangguo Qiu
Organizations
- Canadian Food Inspection Agency
- Chinese Academy of Agricultural Sciences
- Defense Threat Reduction Agency
- National Institute of Allergy and Infectious Diseases
- National Microbiology Laboratory
- Public Health Agency of Canada