RanDeL-Seq: a High-Throughput Method to Map Viral cis - and trans -Acting Elements
Abstract
Recent studies have renewed interest in developing novel antiviral therapeutics and vaccines based on defective interfering particles (DIPs)—a subset of viral deletion mutants that conditionally replicate. Identifying and engineering DIPs require that viral cis - and trans -acting elements be accurately mapped.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 23, 2021
- Source ID
- 10.1128/mbio.01724-20
Entities
People
- Cassandra E. Thompson
- Joshua J. Glazier
- Leor S Weinberger
- Timothy Notton
- Victoria R. Saykally
Organizations
- Gladstone Institutes
- University of California, Berkeley
- University of California, San Francisco