Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection

Abstract

Malaria is a severe and sometimes fatal infectious disease endemic to tropical and subtropical regions. Effective vaccines against malaria-causing Plasmodium parasites remain elusive, and malaria treatments often fail to prevent severe disease.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 26, 2021
Source ID
10.1128/mbio.02424-21

Entities

People

  • Avni S. Gupta
  • Crystal L. Richards
  • David Schneider
  • Frank C. Gherardini
  • Michelle M Lissner
  • Nicole D. Hryckowian
  • Victoria Chevee

Organizations

  • National Institutes of Health
  • National Science Foundation
  • Stanford University

Tags

Fields of Study

  • Medicine

Readers

  • Atmospheric Science/Meteorology
  • Molecular and Cellular Biology
  • Parasitology and Pharmacology of Malaria.

Technology Areas

  • Biotechnology