Endemic Human Coronavirus Antibody Levels Are Unchanged after Convalescent or Control Plasma Transfusion for Early Outpatient COVID-19 Treatment
Abstract
The relevance of preexisting immunity to the four endemic human coronaviruses in the first week of COVID-19 illness on the outcome of COVID-19 progression stems from the high prevalence of the ehCoV and SARS-CoV-2 coronaviruses. The question has been raised of whether therapeutic convalescent plasma or control plasma containing ehCoV antibodies might alter the outcome of COVID-19 progression to hospitalization.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 28, 2023
- Source ID
- 10.1128/mbio.03287-22
Entities
People
- Aaron A.r. Tobian
- Aarthi Shenoy
- Adam C. Levine
- Amy L. Gawad
- Andrea L Cox
- Andrew H Karaba
- Andrew Pekosz
- Anusha Yarava
- Arturo Casadevall
- Atika Singh
- Barry R. Meisenberg
- Bela Patel
- Benjamin Greenblatt
- Bryan Lau
- Catherine G. Sutcliffe
- Christi E. Marshall
- Colin Foster
- Covid-19 Serologic Studies Consortium
- Daniel Cruser
- Daniel E. Ford
- Daniel F Hanley
- David M. Shade
- David Sullivan
- Donald N. Forthal
- Douglas A. Jabs
- Edward R. Cachay
- Elizabeth S. Allen
- Emily S. Spivak
- Evan Beck
- Evan M Bloch
- Giselle Mosnaim
- J. Robinson Singleton
- James H. Paxton
- Janis E. Blair
- Jay S Raval
- Jean Hammel
- Joann R. Petrini
- Jonathan M. Gerber
- Judith S. Currier
- Karen Lane
- Kelly A. Gebo
- Kevin Oei
- Laura L. Hammitt
- Lawrence J. Appel
- Marieelena Cordisco
- Martin S Zand
- Matthew Abinante
- Michael E Roth
- Moises A. Huamán
- Nichol A. Mcbee
- Nicky Karlen
- Oliver Laeyendecker
- Patrick B. Broderick
- Sabra Klein
- Seble Kessaye
- Sheriza N. Baksh
- Shmuel Shoham
- Shweta Anjan
- Sonya L. Health
- Stephan Ehrhardt
- Thomas J. Gniadek
- Trevor S. Johnston
- Valerie C. Cluzet
- William Rausch
- Yuriko Fukuta
Organizations
- Johns Hopkins Bloomberg School of Public Health
- Johns Hopkins University
- National Institute of Allergy and Infectious Diseases
- National Institutes of Health
- United States Department of Defense