Comparative Genomics of Bacteroides fragilis Group Isolates Reveals Species-Dependent Resistance Mechanisms and Validates Clinical Tools for Resistance Prediction
Abstract
Anaerobic infections present unique challenges in terms of detecting and identifying the etiologic agent and selecting the optimal antimicrobial therapy. Antimicrobial resistance is increasing in anaerobic pathogens, and it is critical to understand the prevalence and mechanisms of resistance to commonly prescribed antimicrobial therapies.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 22, 2022
- Source ID
- 10.1128/mbio.03603-21
Entities
People
- Carey-Ann D Burnham
- Gautam Dantas
- Meghan A. Wallace
- Miranda J Wallace
- Sophonie Jean
Organizations
- Congressionally Directed Medical Research Programs
- National Cancer Institute
- National Institute of Allergy and Infectious Diseases
- Ohio State University
- United States Agency for Healthcare Research and Quality
- Washington University School of Medicine
- Washington University in St. Louis