Rift Valley Fever Virus Infection Causes Acute Encephalitis in the Ferret

Abstract

Animal models of viral disease are very important for understanding how viruses make people sick and for testing out drugs and vaccines to see if they can prevent disease. In this study, we identify the ferret as a model of encephalitis caused by Rift Valley fever virus (RVFV). This novel model will allow researchers to evaluate ways to prevent RVFV encephalitis.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 28, 2020
Source ID
10.1128/msphere.00798-20

Entities

People

  • Amy L. Hartman
  • Anita McElroy
  • Dominique J. Barbeau
  • Ed Klein
  • Joseph R. Albe
  • Natasha L. Tilston-lunel
  • Seema S. Lakdawala
  • Sham Nambulli
  • W Paul Duprex

Organizations

  • Burroughs Wellcome Fund
  • National Institutes of Health
  • UPMC Children's Hospital of Pittsburgh
  • University of Pittsburgh

Tags

Readers

  • Oncology
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology