Characterization of a 2016-2017 Human Seasonal H3 Influenza A Virus Spillover Now Endemic to U.S. Swine

Abstract

H3.2010.2 is a new phylogenetic clade of H3N2 circulating in swine that became established after the spillover of a human seasonal H3N2 from the 2016–2017 influenza season. The novel H3.2010.2 transmitted and adapted to the swine host and demonstrated reassortment with internal genes from strains endemic to pigs, but it maintained human-like HA and NA.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 23, 2022
Source ID
10.1128/msphere.00809-21

Entities

People

  • Aditi Sharma
  • Amy L Vincent
  • Carine K. Souza
  • Ganwu Li
  • Jianqiang Zhang
  • Karen Harmon
  • Michael A. Zeller
  • Phillip C Gauger
  • Tavis K Anderson

Organizations

  • Agricultural Research Service
  • Iowa State University
  • National Institute of Allergy and Infectious Diseases
  • Oak Ridge Institute for Science and Education

Tags

Fields of Study

  • Biology

Readers

  • Immunology
  • Microbial Pathology
  • Vector-Borne Disease and Entomology