Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns
Abstract
Deblur provides a rapid and sensitive means to assess ecological patterns driven by differentiation of closely related taxa. This algorithm provides a solution to the problem of identifying real ecological differences between taxa whose amplicons differ by a single base pair, is applicable in an automated fashion to large-scale sequencing data sets, and can integrate sequencing runs collected over time.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 21, 2017
- Source ID
- 10.1128/msystems.00191-16
Entities
People
- Amnon Amir
- Antonio González
- Daniel McDonald
- Embriette R. Hyde
- Eric P. Kightley
- Evguenia Kopylova
- James T. Morton
- Jose A. Navas-molina
- Luke R Thompson
- Rob Knight
- Zhenjiang Zech Xu
Organizations
- Alfred P. Sloan Foundation
- Broad Institute
- Congressionally Directed Medical Research Programs
- Crohn's & Colitis Foundation of America
- Kenneth Rainin Foundation
- Laureate Institute for Brain Research
- National Institutes of Health
- National Multiple Sclerosis Society
- National Science Foundation
- Office of Naval Research
- United States Department of Justice
- United States – Israel Binational Science Foundation
- University of California, San Diego
- University of California, San Francisco
- University of Colorado Boulder
- Washington University in St. Louis