Epidemiology of Plasmid Lineages Mediating the Spread of Extended-Spectrum Beta-Lactamases among Clinical Escherichia coli
Abstract
The increasing incidence of nosocomial infections with extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli represents a significant threat to public health, given the limited treatment options available for such infections. The rapid ESBL spread is suggested to be driven by localization of the resistance genes on conjugative plasmids.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 26, 2022
- Source ID
- 10.1128/msystems.00519-22
Entities
People
- Bejan Mahmud
- Carey-Ann D Burnham
- Carol E. Muenks
- Cristina Lanzas
- David A. Rasmussen
- Erik R. Dubberke
- Gautam Dantas
- Kelly Alvarado
- Kimberly A. Reske
- Meghan A. Wallace
Organizations
- Congressionally Directed Medical Research Programs
- National Institute of Allergy and Infectious Diseases
- National Institute of Diabetes and Digestive and Kidney Diseases
- North Carolina State University
- United States Agency for Healthcare Research and Quality
- Washington University School of Medicine
- Washington University in St. Louis