Global Transcriptional Response of Escherichia coli Exposed In Situ to Different Low-Dose Ionizing Radiation Sources
Abstract
Escherichia coli strain DH10β, a well-characterized model bacterium, was subjected to short-term (1-day) and long-term (15-day) exposures to three different in situ radiation sources comprised of radionuclides relevant to nuclear activities to induce a measurable and identifiable genetic response. We found E. coli had both common and unique responses to the three exposures studied, suggesting both dose rate- and radionuclide-specific effects.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 27, 2023
- Source ID
- 10.1128/msystems.00718-22
Entities
People
- Lisa Manglass
- Mark Blenner
- Molly Wintenberg
- Nicole E. Martinez
Organizations
- Clemson University
- Defense Threat Reduction Agency
- Francis Marion University
- University of Delaware