High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response

Abstract

Infectious diseases caused by viral pathogens exacerbate health care and economic burdens. Numerous viral biomolecules suppress the human innate immune system, enabling viruses to evade an immune response from the host.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 26, 2022
Source ID
10.1128/msystems.01466-21

Entities

People

  • Colin Molloy
  • Debora S. Marks
  • Erika J. Olson
  • H. Sloane Weiss
  • Jeffrey C Way
  • John I Glass
  • Jérôme Zürcher
  • Nathan J. Rollins
  • Pamela Silver
  • Peter D. Koch
  • Pia Mach
  • Roger L. Chang
  • Tae Yeon Yoo
  • Tai L. Ng
  • Tim Mitchison
  • Timothy Z. Chang
  • Tobias Meisinger
  • Trenton Bricken
  • Yukiye Koide

Organizations

  • Harvard Medical School
  • Harvard University
  • Intelligence Advanced Research Projects Activity
  • J. Craig Venter Institute
  • National Institutes of Health
  • Open Philanthropy Project

Tags

Fields of Study

  • Medicine

Readers

  • Nanoscale Plasmonic Nanotechnology
  • Oncology
  • Virology (or Medical Virology).