A tRNA-Acetylating Toxin and Detoxifying Enzyme in Mycobacterium tuberculosis
Abstract
The global rise in antibiotic-resistant tuberculosis has prompted an urgent search for new drugs. Toxin-antitoxin (TA) systems allow bacteria to adapt rapidly to environmental changes, and Mycobacterium tuberculosis encodes more TA systems than any known pathogen.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 29, 2022
- Source ID
- 10.1128/spectrum.00580-22
Entities
People
- Alexander M. J. Hall
- Charles L. Dulberger
- Eric Rubin
- Francesca G. Tomasi
- Jessica T. P. Schweber
- Kerry Mcgowen
- Qingyun Liu
- Sarah Fortune
- Sophie Helaine
Organizations
- Harvard Medical School
- Harvard University
- National Institute of Allergy and Infectious Diseases
- United States Department of Defense