A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid
Abstract
Antibiotic resistance poses a critical problem to human health and decreases the utility of these lifesaving drugs. Of particular concern is the “superbug” methicillin-resistant Staphylococcus aureus (MRSA), for which treatment of infection requires the use of last-line antibiotics, including linezolid.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 31, 2022
- Source ID
- 10.1128/spectrum.00583-22
Entities
People
- Alexander Wright
- Christopher James Stubenrauch
- David W Lupton
- Kher-shing Tan
- Laura Perlaza-jiménez
- Matthew Belousoff
- Rachel M. Johnson
- Rebecca S. Bamert
- Sarah J. Piper
- Trevor Lithgow
Organizations
- Australian Research Council
- Congressionally Directed Medical Research Programs
- Monash University
- Monash University Faculty of Pharmacy and Pharmaceutical Sciences
- National Health and Medical Research Council