Malaria Molecular Surveillance in the Peruvian Amazon with a Novel Highly Multiplexed Plasmodium falciparum AmpliSeq Assay

Abstract

While the power of next-generation sequencing technologies to inform and guide malaria control programs has become broadly recognized, the integration of genomic data for operational incorporation into malaria surveillance remains a challenge in most countries where malaria is endemic. The main obstacles include limited infrastructure, limited access to high-throughput sequencing facilities, and the need for local capacity to run an in-country analysis of genomes at a large-enough scale to be informative for surveillance.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 13, 2023
Source ID
10.1128/spectrum.00960-22

Entities

People

  • Anna Rosanas-Urgell
  • Carlos Fernandez-miƱope
  • Christopher Delgado-ratto
  • Dionicia Gamboa
  • Eduard Rovira-vallbona
  • Hugo O. Valdivia
  • Jean-pierre Van Geertruyden
  • Johanna Helena Kattenberg
  • Lidia Llacsahuanga Allcca
  • Norbert J. Van Dijk
  • Pieter Guetens
  • Pieter Monsieurs

Organizations

  • Cayetano Heredia University
  • Enabel
  • Institute of Tropical Medicine Antwerp
  • University of Antwerp

Tags

Fields of Study

  • Biology

Readers

  • Enterprise Information Systems Architecture and Joint Command Capability Interoperability Support.
  • Molecular Genetics
  • Parasitology and Pharmacology of Malaria.