Expression of Human Endogenous Retrovirus Group K (HERV-K) HML-2 Correlates with Immune Activation of Macrophages and Type I Interferon Response
Abstract
The human endogenous retrovirus group K subgroup, HML-2, is known to be elevated in a long list of inflammation-associated diseases. However, a clear mechanism for HML-2 upregulation in response to inflammation has not been defined.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 13, 2023
- Source ID
- 10.1128/spectrum.04438-22
Entities
People
- Eric Russ
- Natallia Mikhalkevich
- Sergey Iordanskiy
Organizations
- Congressionally Directed Medical Research Programs
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Uniformed Services University of the Health Sciences