Neisseria gonorrhoeae Coinfection during Chlamydia muridarum Genital Latency Does Not Modulate Murine Vaginal Bacterial Shedding

Abstract

Our work builds upon the limited understanding of C. muridarum / N. gonorrhoeae coinfection. Previously, N. gonorrhoeae infection of mice with acute (actively replicating) vaginal C. muridarum infection was shown to increase recovery of viable vaginal N. gonorrhoeae and vaginal PMNs, with no effect on C. muridarum vaginal shedding (R. A. Vonck et al., Infect Immun 79:1566–1577, 2011).

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 15, 2023
Source ID
10.1128/spectrum.04500-22

Entities

People

  • Ann E. Jerse
  • Barbara Prähauser
  • Bernadetta Tarigan
  • Cory Ann Leonard
  • Delia Onorini
  • Nicole Borel
  • Regenia Phillips Campbell
  • Robert V. Schoborg
  • Theresa Pesch

Organizations

  • East Tennessee State University James H. Quillen College of Medicine
  • Swiss National Science Foundation
  • Uniformed Services University of the Health Sciences
  • University of Zurich

Tags

Readers

  • Immunology
  • Infectious Disease/Epidemiology