Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline

Abstract

Drug resistance necessitates the development of new antimalarial drugs. It is important to assess the activities of compounds under development against parasites now causing disease in Africa, where most malaria cases occur, and to determine if mutations in these parasites may limit the efficacies of new agents.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 15, 2023
Source ID
10.1128/spectrum.05236-22

Entities

People

  • Alasdair Smith
  • Barbara Forte
  • Benjamin Blasco
  • David Giesbrecht
  • Hiroki Kano
  • Jeffrey A. Bailey
  • Jennifer Legac
  • Martin Okitwi
  • Maëlle Duffey
  • Melissa D Conrad
  • Oriana Kreutzfeld
  • Oswald Byaruhanga
  • Ozkan Aydemir
  • Patrick K. Tumwebaze
  • Peter Campbell
  • Philip J Rosenthal
  • Roland A. Cooper
  • Samuel L. Nsobya
  • Stephanie A. Rasmussen
  • Stephen Orena
  • Thomas Katairo

Organizations

  • Brown University
  • Dominican University of California
  • Infectious Diseases Research Collaboration
  • Istituto Superiore di Sanità
  • Medicines for Malaria Venture
  • Mitsubishi Tanabe Pharma
  • University of California, San Francisco
  • University of Dundee
  • University of Massachusetts Medical School

Tags

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Molecular and genetic basis of cancer.
  • Parasitology and Pharmacology of Malaria.