Peripheral blood gene expression profiling shows predictive significance for response to mycophenolate in systemic sclerosis-related interstitial lung disease
Abstract
To characterise the peripheral blood cell (PBC) gene expression changes ensuing from mycophenolate mofetil (MMF) or cyclophosphamide (CYC) treatment and to determine the predictive significance of baseline PBC transcript scores for response to immunosuppression in systemic sclerosis (SSc)-related interstitial lung disease (ILD).
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 21, 2022
- Source ID
- 10.1136/annrheumdis-2021-221313
Entities
People
- Donald P. Tashkin
- Elizabeth R Volkmann
- Holly Wilhalme
- Marka A. Lyons
- Michael D. Roth
- Shervin Assassi
- W. Jim Zheng
- Xuan Wang
Organizations
- Congressionally Directed Medical Research Programs
- National Center for Advancing Translational Sciences
- National Heart, Lung, and Blood Institute
- National Institute of Arthritis and Musculoskeletal and Skin Diseases