Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis

Abstract

The Collaborative Cross (CC) is a mouse population model with diverse and reproducible genetic backgrounds used to identify novel disease models and genes that contribute to human disease. Since spontaneous tumour susceptibility in CC mice remains unexplored, we assessed tumour incidence and spectrum.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 06, 2019
Source ID
10.1136/gutjnl-2018-316691

Entities

People

  • Antoine M Snijders
  • Carolina M Rojas
  • Colin Brislawn
  • David W. Threadgill
  • Janet K Jansson
  • Jian-Hua Mao
  • Kimberly L Wahl
  • Kuang-yu Jen
  • Pin Wang
  • Qi Sun
  • Sasha A Langley
  • Susan E. Celniker
  • Ting Wang
  • Xiangshan Fan
  • Xiaoping Zou
  • Yan-xia Zhou
  • Yunshan Wang

Organizations

  • Lawrence Berkeley National Laboratory
  • National Institutes of Health
  • National Natural Science Foundation of China
  • Office of Naval Research

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology