Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma
Abstract
Intrahepatic cholangiocarcinoma (ICC)—a rare liver malignancy with limited therapeutic options—is characterised by aggressive progression, desmoplasia and vascular abnormalities. The aim of this study was to determine the role of placental growth factor (PlGF) in ICC progression.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 11, 2021
- Source ID
- 10.1136/gutjnl-2020-322493
Entities
People
- Alexander Quaas
- Andrew X Zhu
- Aya Matsui
- Dan G Duda
- Daniel H Schanne
- Emilie Mamessier
- Hadi T. Nia
- Hiroto Kikuchi
- Irinel Popescu
- Ivy Chen
- Jiang Chen
- Kazumichi Kawakubo
- Koetsu Inoue
- Kohei Shigeta
- Lance L. Munn
- Masaaki Iwasaki
- Mitesh J. Borad
- Mohammad R Nikmaneshi
- Nabeel Bardeesy
- Patrick S Plum
- Rakesh Jain
- Rakesh R Ramjiawan
- Sebastian Klein
- Shuichi Aoki
- Shuji Kitahara
- Simona Dima
- Slim Sassi
- Stefan Halvorsen
- T Yau
- Tai Hato
- Theodore S Hong
- Tyge Ce Schmidt
- Xianfeng Chen
Organizations
- Alexander von Humboldt Foundation
- Astellas Foundation for Research on Metabolic Disorders
- Cancéropôle PACA
- National Cancer Institute
- National Foundation for Cancer Research
- Uehara Memorial Foundation
- United States Department of Defense