Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer
Abstract
Surveillance tools for early cancer detection are suboptimal, including hepatocellular carcinoma (HCC), and biomarkers are urgently needed. Extracellular vesicles (EVs) have gained increasing scientific interest due to their involvement in tumour initiation and metastasis; however, most extracellular RNA (exRNA) blood-based biomarker studies are limited to annotated genomic regions.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 28, 2021
- Source ID
- 10.1136/gutjnl-2021-325036
Entities
People
- Amanda Craig
- Amon Asgharpour
- Ash Tewari
- Augusto Villanueva
- Behnam Saberi
- Benjamin Wunsch
- Bojan Losic
- Carlos Cordon-cardo
- Dan Han
- Delia D'Avola
- Douglas Dieterich
- Edgar Gonzalez‐Kozlova
- Gabriela Hernandez-Meza
- Gustavo Stolovitzky
- Ismail Labgaa
- Jennifer E L Diaz
- Johann von Felden
- Josep M. Llovet
- Joshua T. Smith
- Kimaada Allette
- Mehmet Eren Ahsen
- Myron Schwartz
- Navneet Dogra
- Parissa Tabrizian
- Paula Restrepo
- Philipp K. Haber
- Reena Olsen
- Robert Sebra
- Stacey Gifford
- Sungcheol Kim
- Teresa Garcia-Lezana
- Xintong Chen
Organizations
- Agency for Administration of University and Research
- Asociación Española para el Estudio del Hígado
- European Commission
- German Research Foundation
- Israel National Road Safety Authority
- National Cancer Institute
- National Institutes of Health
- Samuel Waxman Cancer Research Foundation
- Spanish Association Against Cancer
- Swiss National Science Foundation
- United States Department of Defense
- University Medical Center Hamburg-Eppendorf