A mechanism by which gut microbiota elevates permeability and inflammation in obese/diabetic mice and human gut

Abstract

Ample evidence exists for the role of abnormal gut microbiota composition and increased gut permeability (‘leaky gut’) in chronic inflammation that commonly co-occurs in the gut in both obesity and diabetes, yet the detailed mechanisms involved in this process have remained elusive.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 22, 2023
Source ID
10.1136/gutjnl-2022-327365

Entities

People

  • Ambuj Kumar
  • Bo Wang
  • Christian Brechot
  • Cristina M. Furdui
  • Dalane W. Kitzman
  • Hariom L. Yadav
  • Jared Rejeski
  • Jingzhong Ding
  • Shalini Jain
  • Sidharth P Mishra
  • Subhash Taraphder

Organizations

  • National Institutes of Health
  • United States Department of Defense

Tags

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Educational Psychology
  • Molecular and Cellular Biology