CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of TH1 and TH9 cells
Abstract
While stimulator of interferon genes (STING) activation in innate immune cells of the tumor microenvironment can result in CD8 T cell-dependent antitumor immunity, whether STING signaling affects CD4 T-cell responses remains elusive.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2022
- Source ID
- 10.1136/jitc-2021-003459
Entities
People
- Alvaro Baeza Garcia
- Andréa Melis
- Aurélie Roussey
- Bernhard Ryffel
- Cassandre Pignol
- Corentin Richard
- Daria Vinokurova
- Eric R Nelson
- Frédérique Végran
- Isis Benoit-Lizon
- Lionel Apetoh
- Ludivine Dal Zuffo
- Pauline Soulas-sprauel
- Raphaël Carapito
- Richard A. Flavell
- Romain Boidot
- Sayyed Hamed Shahoei
- Stéphane Giorgiutti
- Thaiz Rivera Vargas
- Tiffany Martin
- Toby Lawrence
- Élise Jacquin
Organizations
- Agence Nationale de la Recherche
- European Regional Development Fund
- European Research Council
- Fondation ARC pour la recherche sur le cancer
- Fondation de France
- Fondation pour la Recherche Médicale
- National Cancer Institute
- United States Department of Defense