Tumor and immune remodeling following radiotherapy in human renal cell carcinoma
Abstract
Studies evaluating peripheral patient samples show radiation can modulate immune responses, yet the biological changes in human tumors particularly at the cellular level remain largely unknown. Here, we address how radiation treatment shapes the immune compartment and interactions with cancer cells within renal cell carcinoma (RCC) patient tumors.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 01, 2023
- Source ID
- 10.1136/jitc-2022-006392
Entities
People
- Adil Khan
- Alexis Conway
- Anurag K Singh
- Brianna J Wasik
- Elizabeth A. Repasky
- Jacky Chow
- Jason B Muhitch
- Kah Teong Soh
- Madeline Gaudieri
- Paul K Wallace
- Scott I Abrams
- Thomas Schwaab
Organizations
- National Cancer Institute
- National Center for Advancing Translational Sciences
- United States Department of Defense