Relationship between intrinsic network connectivity and psychiatric symptom severity in functional seizures
Abstract
Traumatic brain injury (TBI) may precipitate the onset of functional seizures (FSs). Many patients with FS report at least one prior TBI, and these patients typically present with more severe psychiatric comorbidities. TBI and psychopathology are linked to changes in neural network connectivity, but their combined effects on these networks and relationship to the effects of FS remain unclear. We hypothesised that resting-state functional connectivity (rsFC) would differ between patients with FS and TBI (FS+TBI) compared with TBI without FS (TBI only), with variability only partially explained by the presence of psychopathology.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 27, 2022
- Source ID
- 10.1136/jnnp-2022-329838
Entities
People
- Adam M Goodman
- Jane B. Allendorfer
- Jerzy P Szaflarski
- Noah S Philip
- Pranav Kakulamarri
- Rodolphe Nenert
- Stephen Correia
- W Curt LaFrance, Jr.
Organizations
- United States Department of Defense