Age of thawed plasma does not affect clinical outcomes or biomarker expression in patients receiving prehospital thawed plasma: a PAMPer secondary analysis

Abstract

Prehospital plasma administration during air medical transport reduces the endotheliopathy of trauma, circulating pro-inflammatory cytokines, and 30-day mortality among traumatically injured patients at risk of hemorrhagic shock. No clinical data currently exists evaluating the age of thawed plasma and its association with clinical outcomes and biomarker expression post-injury.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 01, 2021
Source ID
10.1136/tsaco-2020-000648

Entities

People

  • Brian G. Harbrecht
  • Brian J. Daley
  • Brian S. Zuckerbraun
  • Danielle S Gruen
  • Frances Guyette
  • Herb A. Phelan
  • Jakob Stensballe
  • Jason L. Sperry
  • Jeffrey Claridge
  • Joshua B. Brown
  • Katherine Moll Reitz
  • Mark H. Yazer
  • Matthew D Neal
  • Pär I Johanssen
  • Richard S. Miller
  • Yoram Vodovotz

Organizations

  • National Heart, Lung, and Blood Institute
  • National Institute on Aging
  • United States Army Medical Research and Development Command

Tags

Fields of Study

  • Medicine

Readers

  • Immunology
  • Neurotrauma and Rehabilitation Medicine.
  • Trauma Surgery or Emergency Medicine.