A three-dimensional discrete model for approximating the deformation of a viral capsid subjected to lying over a flat surface in the static and time-dependent case

Abstract

In this paper, we present a three-dimensional discrete model governing the deformation of a viral capsid, modelled as a regular icosahedron and subjected not to cross a given flat rigid surface on which it initially lies in correspondence of one vertex only. First, we set up the model in the form of a set of variational inequalities posed over a non-empty, closed and convex subset of a suitable space. Second, we show the existence and uniqueness of the solution for the proposed model. Third, we numerically test this model and we observe that the outputs of the numerical experiments comply with physics. Finally, we establish the existence of solutions for the corresponding time-dependent version of the obstacle problem under consideration.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 23, 2022
Source ID
10.1142/s0219530522400024

Entities

People

  • Bogdan Dragnea
  • Kristen White
  • Paolo Piersanti
  • Roger Temam

Organizations

  • Army Research Office
  • Indiana University
  • Indiana University Bloomington
  • National Science Foundation

Tags

Fields of Study

  • Mathematics

Readers

  • Calculus or Mathematical Analysis
  • Computational Modeling and Simulation
  • Graph Algorithms and Convex Optimization.

Technology Areas

  • Space