Defecation induced by stimulation of sacral S2 spinal root in cats
Abstract
This study in cats determined the optimal stimulation parameters and the spinal segment for sacral spinal root stimulation to induce colon contraction. The results have significant implications for design of a novel neuromodulation device to restore defecation function after spina cord injury (SCI) and for optimizing sacral neuromodulation parameters to treat non-SCI people with chronic constipation.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 01, 2021
- Source ID
- 10.1152/ajpgi.00269.2021
Entities
People
- Bing Shen
- Changfeng Tai
- Christopher Chermansky
- Jianan Jian
- Jicheng Wang
- Jonathan Beckel
- Khari Goosby
- Travis Hannan
- William C. De Groat
- William Wang
- Zhijun Shen
Organizations
- University of Pittsburgh