Mechanisms that limit regression of myocardial fibrosis following removal of left ventricular pressure overload

Abstract

In this study, a murine model demonstrated persistent interstitial fibrosis and myocardial stiffness following alleviation of pressure overload.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 01, 2022
Source ID
10.1152/ajpheart.00148.2022

Entities

People

  • Amy D Bradshaw
  • An O. Van Laer
  • Catalin F. Baicu
  • Lily S. Neff
  • Mark Karavan
  • Michael R. Zile
  • Ralph H. Johnson
  • Yuhua Zhang

Organizations

  • Medical University of South Carolina
  • National Institute of General Medical Sciences
  • United States Department of Veterans Affairs

Tags

Readers

  • Cardiovascular Physiology
  • Immunology and Pathology
  • Materials Science (Mechanical Engineering).