Reperfused vs. nonreperfused myocardial infarction: when to use which model

Abstract

There is a lack of understanding in the cardiac remodeling field regarding the use of nonreperfused myocardial infarction (MI) and reperfused MI in animal models of MI. This Perspectives summarizes the consensus of the authors regarding how to select the optimum model for your experiments and is a part of ongoing efforts to establish rigor and reproducibility in cardiac physiology research.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 01, 2021
Source ID
10.1152/ajpheart.00234.2021

Entities

People

  • Caitlin C. O’meara
  • Crystal M Ripplinger
  • Francis G. Spinale
  • Ganesh V Halade
  • Jonathan A. Kirk
  • Keith R. Brunt
  • Kristine Y DeLeon-Pennell
  • Lisandra E de Castro Brás
  • Merry L. Lindsey
  • Nikolaos G Frangogiannis
  • Petra Kleinbongard
  • Zamaneh Kassiri

Organizations

  • Albert Einstein College of Medicine
  • Canadian Institutes of Health Research
  • Dalhousie University
  • East Carolina University
  • Loyola University Chicago
  • Medical College of Wisconsin
  • Medical University of South Carolina
  • Office of Extramural Research
  • United States Department of Defense
  • United States Department of Veterans Affairs
  • University of Alberta
  • University of California, Davis
  • University of Nebraska Medical Center
  • University of South Carolina
  • University of South Florida

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Systems Analysis and Design