Impact of successive exertional heat injuries on thermoregulatory and systemic inflammatory responses in mice
Abstract
Mice undergoing repeated exertional heat injuries, within 1 wk of an initial heat injury, appear to have some protective adaptations. During the second exertional heat injury, mice were able to run longer and sustain higher body temperatures before collapse. Despite this, the mice undergoing a second exertional heat injury were more resilient to the heat as evidenced by attenuated minimum body temperature, higher HPS70 (serum and liver), lower corticosterone, and lower FABP2.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 01, 2021
- Source ID
- 10.1152/japplphysiol.00160.2021
Entities
People
- Aaron Caldwell
- Jermaine A. Ward
- Kentaro Oki
- Lisa R. Leon
- Mark L. Plamper
- Michelle A. King
- Shauna M. Ward
- Thomas A. Mayer
Organizations
- United States Army Research Institute of Environmental Medicine