A novel animal model to study delayed resuscitation following traumatic hemorrhage
Abstract
A focus of combat casualty care research is to develop treatment where full resuscitation after hemorrhage is delayed. However, animal models of combat-related hemorrhagic shock in which to determine physiological outcomes of such delays and explore potential treatment for golden hour extension are lacking. In this study, we filled this knowledge gap by establishing a traumatic shock model with reproducible development of AKI and shock-related complications determined by the time of resuscitation.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 01, 2022
- Source ID
- 10.1152/japplphysiol.00335.2022
Entities
People
- Alfredo S. Calderon
- Carmen Hinojosa-Laborde
- Harold G. Klemcke
- Kathy L. Ryan
- Lusha Xiang
- Sandra C. Becerra
Organizations
- United States Army Institute of Surgical Research